Cell Regulation Quotes

The number of cells in our bodies is defined by an equilibrium of opposing forces: mitosis adds cells, while programmed cell death removes them. Just as too much cell division can lead to a pathological increase in cell number, so can too little cell death.

You've got to get away from the idea cancer is a disease to be cured. It's not a disease really. The cancer cell is your own body, your own cells, just misbehaving and going a bit wrong, and you don't have to cure cancer. You don't have to get rid of all those cells. Most people have cancer cells swirling around inside them all the time and mostly they don't do any harm, so what we want to do is prevent the cancer from gaining control. We just want to keep it in check for long enough that people die of something else.

Cancer cells have a lot of other things that are really wrong with them, and we should never forget that these are cells that have become deaf to all the signals that the body sends out, such as you can multiply a certain amount, you can be in a certain place in the body, where to stay, where to move, and so on.

We know cancer is caused ultimately via a link between the environment and genes. There are genes inside cells that tell cells to grow and the same genes tell cells to stop growing. When you deregulate these genes, you unleash cancer. Now, what disrupts these genes? Mutations.

Cancer is really a DNA disease... We have these certain genes that prevent our cells from growing out of control at the expense of the body. And it's a pretty good, robust system. But if a couple of these genes fail, then that's when cancer starts, and cells start growing out of control.

I am interested in how cells know what they are and how they should behave in their proper place in the body.

Proteins are constantly being degraded. Therefore, simultaneous production of proteins is required.

I am not surprised that other gases may participate in cellular signaling and regulation. Our early work with nitric oxide was just the beginning. I'm sure more will be discovered.