Cancer Biology Quotes

When I was at Stanford, I was actually in the cancer biology program, but I mostly focused on infectious disease.

It will be in the convergence of evolutionary biology, developmental biology and cancer biology that the answer to cancer will lie. Nor will this confluence be a one-way street.

Although the elusive 'cure' may be a distant dream, understanding the true nature of cancer will enable it to be better controlled and less menacing.

Cancer is not something confined to human beings. It's found in all multi cellular organisms where the adult cells proliferate, so it's widespread in the biosphere. It's a phenomenon that is deeply related to the history of life itself, so by studying cancer I think we can illuminate the history of life itself and vice versa.

Cancer is not just a dividing cell. It's a complex disease: It invades, it metastasizes, it evades the immune system.

In the laboratory, we call this the six-degrees-of-separation-from-cancer rule: you can ask any biological question, no matter how seemingly distant-what makes the heart fail, or why worms age, or even how birds learn songs-and you will end up, in fewer than six genetic steps, connecting with a proto-oncogene or tumor suppressor.

Cancer cells have a lot of other things that are really wrong with them, and we should never forget that these are cells that have become deaf to all the signals that the body sends out, such as you can multiply a certain amount, you can be in a certain place in the body, where to stay, where to move, and so on.

Cancer is really a DNA disease... We have these certain genes that prevent our cells from growing out of control at the expense of the body. And it's a pretty good, robust system. But if a couple of these genes fail, then that's when cancer starts, and cells start growing out of control.

It turns out that the very genes that turn on in cancer cells perform vital functions in normal cells. In other words, the very genes that allow our embryos to grow or our brains to grow, our bodies to grow, if you mutate them, if you distort them, then you unleash cancer.

Cancer was not disorganized chromosomal chaos. It was organized chromosomal chaos

If there's a seminal discovery in oncology in the last 20 years, it's that idea that cancer genes are often mutated versions of normal genes.

The most dangerous cancer cells are actually the ones that are more like stem cells, which have this ability to produce themselves over and over again. More and more cancer biologists say stem-cell-like cells in cancers are the most dangerous.

Cancer is a disease of the genome. And that's what happens. You make mistakes in a cell somewhere in your body that causes it to start to grow when it should've stopped, and that's cancer. And those mistakes are mistakes of DNA.

Nearly every one of the genes that turns out to be a key player in cancer has a vital role in the normal physiology of an organism. The genes that enable our brains and blood cells to develop are implicated in cancer.

From some dilatory reading in the early 1960s, I knew enough about viruses and their association with tumors in animals to understand that they might provide a relatively simple entry into a problem as complex as cancer.

There is a duality in recognising what an incredible disease it is - in terms of its origin, that it emerges out of a normal cell. It's a reminder of what a wonderful thing a normal cell is. In a very cold, scientific sense, I think a cancer cell is a kind of biological marvel.