Autophagy Quotes

The brain that doesn't feed itself, eats itself.

If you asked me what caused aging, I would say free radicals and molecules, which spontaneously shift and form and cause damage in all our cells and genes. The body usually repairs and replaces the damage in these genes. But as you get older, the aging clock turns down those defenses.

If I'm not hungry and I'm busy, I am quite happy to skip a meal. It's informal intermittent fasting. I feel strongly that this is one of the strongest areas of longevity research.

The number of cells in our bodies is defined by an equilibrium of opposing forces: mitosis adds cells, while programmed cell death removes them. Just as too much cell division can lead to a pathological increase in cell number, so can too little cell death.

Because of the relationship between programmed cell death and human disease, the identification of the genes and proteins that function in the process of programmed cell death has provided new targets for possible intervention in a broad diversity of disorders.

Lower caloric exposure and episodic fasting can extend the life span of all animals, the longer we spend in the catabolic state, the longer we live.

Fasting, or intermittent fasting, gives us an opportunity to really get all the best cells all the time and that's what we all want.

If a portion of a redwood is rotting, the redwood will send roots into its own form and draw nutrients out of itself as it falls apart. If we had redwood-like biology, if we got a touch of gangrene in our arm, then we could just, you know, extract the nutrients and the moisture out of it until it fell off.

We discovered a mechanism which is like the garbage machine of the body. We need to remove damaged proteins and create new ones in their place, and we discovered the machine that does this.

Periodic fasting can help clear up the mind and strengthen the body and the spirit.

I only eat one meal a day. Lunch, not dinner.

You want to shock the body and not be constant. Intermittent fasting is an increasingly popular way: Skip breakfast, for example. Also lifting weights, losing your breath from exercise and alternating between hot and cold temperatures. We think these measures will only get us to 100 to 122 years old. That's our natural lifespan.