JOHNNY GALECKI

In a series, you really need to stay open-minded. It's not like a play or a film, where you can create and fully commit to your character's back-story.

You get to a certain point - gratefully - when you're out of your twenties, and you realize how fleeting life is. So, it becomes important to feel as if the people in your life know exactly how you feel about them at all times.

I used to know Jennifer Love Hewitt. We lived in the same apartment building when I was about... jeez, I guess it was when I was doing 'Christmas Vacation', so I was about 13 or 14.

It took me a long time to realize that to walk around without a certain amount of belief in myself, to walk onto a job with my tail between my legs, wasn't behooving anyone else.

As they say, there are two rules in improv: Never say no, and never ask why. When another actor asks 'Why?' or says no to something you're suggesting, then it's very clear that they're putting the onus on you, because they're not comfortable with it themselves.

We can't really do any improv on 'The Big Bang' because we don't understand a lot of what the dialogue means to begin with, because of the physics jargon.

I read the papers, and I watch the news a lot. I watch 'Dateline' and '48 Hours.' And I think we have a tendency to become terrified of one another, thinking that there is a serial killer that is on either side of you.

I'm not at all competitive. I'd rather play Solitaire than ping-pong.

Right now, I'm very healthy. I have no vices left. Except sugary breakfast cereal. And absinthe, of course.

Scientists are not these guys in lab coats deep in the inner bowels of universities and hospitals with their Bunsen burners. They're the people molding the culture that we live in, the future of our culture, and the technology we rely on every day.

Comedy is similar to hockey... in only one way. You get a lot of credit for assists. So I try to serve whatever the intention is, be it the joke or the story or the scene or the moment or the kiss, even if it's not my joke or moment.

'Entourage' is a great show, but it's fantasy. I spent my twenties in L.A. in this business, and my life didn't look anything like that. 'Big Bang' reflects a side of men that is rarely shown. We see their flaws - all of them.

I don't know what to do with myself between films. I end up doing unhealthy things like shopping or drinking. I'm pretty schizophrenic about it.

I love to work. I absolutely love to work.

I bought a little hideaway up north, so I'll ship my motorcycle up there. It's much less dangerous than West Hollywood.

There is that stereotype of a nerd with the high pants and pocket protector and that kind of thing. That can sustain comedy for maybe a movie - hence the 'Revenge of the Nerds' franchise - but not for hopefully years on the air. It's a sight gag, not a story.

People are complicated; you put two of them together and it's generally a mess, but hopefully a beautiful mess.

We didn't have a TV because we didn't have a whole lot of money. My parents would have their friends over - their friends who thought, 'How can you live without a TV?'

You know, I read the papers and I watch the news a lot. I watch 'Dateline' and '48 Hours'. And I think we have a tendency to become terrified of one another, thinking that there is a serial killer that is on either side of you.

I know a lot of incredibly, profoundly talented, skilled people that aren't given certain opportunities or any opportunities, and that aren't working.

I was a huge theater geek growing up, and that was not the easiest thing in the world, especially growing up in Chicago, where sports are really the norm. I was always off to the theater at night, from 7 years old on. Friends there in the Midwest who could talk to you about the idiosyncrasies of 'Pippin' were few and far between.

I work in fantasy all day, so when I go home, I want to touch reality.

We've all seen great actors and actresses who are missing a certain chemistry. And it's not about getting along or not getting along.

It's never been a priority for me to concentrate on the likability of the character.

When I'm back home in Chicago, since 'Roseanne' was such a Midwestern, blue-collar show, that's what sticks out in people's minds.