In theory, it is illegal to make the basement into a bureaucratic purgatory. In 1994, for instance, Congress prohibited agencies from making significant changes in a whistleblower's 'working conditions' as punishment for speaking out.
There are some very significant changes in the way the fluids are distributed in our body, the way our heart functions initially, and as well as our bone and muscle.
The Latin American people have become fed up with the 500 year siesta and the lack of opportunity. So they come to the United States. But that is because the leaders of their countries do not do anything to improve the situation…. When Mexican President Fox took office he observed that over half the Mexican population was living in poverty and that he was unlikely to make significant changes during his remaining term in office. That was a sophisticated way of saying to the Mexicans, “Go to the United States!”
It is strange, but true, that the most important turning-points of life often come at the most unexpected times and in the most unexpected ways.
This world is clearly emerging before our eyes. The shifts ahead, the opportunities ahead are massive.
I think it is fair to say that it is under a great deal of stress, and if I am asking for significant changes, it is because the world is going through significant changes.
Business has to change the way it does business, or we will make no significant changes in the way we relate to the earth.
Things that change history tend to be organized.
I still believe we wasted a golden opportunity to make significant changes in our country. I think people in America would have been ready and willing to do it, but the Bush administration took a kind of simplistic, almost moronic approach to it, all because people were so afraid.
You're not a baby boomer if you don't have a visceral recollection of a Kennedy and a King assassination, a Beatles breakup, a U.S. defeat in Vietnam, and a Watergate.
We do not always appreciate the role the Queen has played in one of the most significant changes in the past 60 years: the transformation of Britain into a multi-ethnic, multi-faith society. No one does interfaith better than the Royal family, and it starts with the Queen herself.
If we are ever going to fix our housing affordability crisis, we have to make significant changes to how we plan and construct, and we have to be open to solutions that make it easier and faster to build much-needed housing.
They emphasize the viewpoint that the protracted economic stagnation in Japan derives from incomplete economic adjustments to significant changes in relative prices.
I've had to step up when I was Al Gore's campaign manager. I had to make significant changes as we moved from Washington, D.C. to Tennessee.
In my mind, this is an 'and,' it's not 'either' 'or' or 'but.' Yeah, you can feel a certain way about honoring the flag and the country, and feel that there needs to be some significant changes in the system, regarding racial inequalities.
In the same period, Polish literature also underwent some significant changes. From social-political literature, which had a great tradition and strong motivation to be that way, Polish literature changed its focus to a psychological rather than a social one.
There is a group of entrepreneurs pushing the envelope, government officials that are making significant changes despite the odds, and visionary writers, academics, and colleagues whose work confirms, amplifies, and stretches my own thinking.
There are some things in life that shouldn't be given so much importance, if they don't change what is essential.