In theoretical physics, one can, in principle, work from anyplace as long as one has a computer and Internet connection. So I do not find any disadvantage of being in Allahabad.
I tend to change research direction every few years or so.
But ... the working scientist ... is not consciously following any prescribed course of action, but feels complete freedom to utilize any method or device whatever which in the particular situation before him seems likely to yield the correct answer. ... No one standing on the outside can predict what the individual scientist will do or what method he will follow.
The Weizmann Institute showed me respect and didn't require many administrative tasks, so I was quite independent. I did what I wanted.
As with any large investment, it can be emotionally difficult to abandon a line of research when it isn't working out. But in science, if something isn't working, you have to toss it out and try something else.
If you're a real scientist, you're constantly open to new data. Nothing is ever 100% validated.
Here I was into astronomy, and here into anthropology, and there I go into geology. It was much more fun to be able to research and write about whatever I wanted to.
One of the awesome things about being a writer is that I can research nearly anything - tea? Bubblegum? Ants? Neurology? Chocolate? Textile production? It doesn't matter. It's all productive work.