Genetic Regulation Quotes

With DNA, you have to be able to tell which genes are turned on or off. Current DNA sequencing cannot do that. The next generation of DNA sequencing needs to be able to do this. If somebody invents this, then we can start to very precisely identify cures for diseases.

We have 100 genes or so, which we know we can't knock out without killing the cell, that are of unknown structure.

Like other new and potentially powerful technologies, gene editing raises legitimate questions and understandable concerns about possible risks and misuse. How, then, should the technology be regulated? Rules developed decades ago for other forms of genetic engineering do not necessarily fit. Noting that gene-edited organisms are not transgenic, the U.S. Department of Agriculture has reasonably concluded that genetically edited plants are like plants with naturally occurring mutations and thus are not subject to special regulations and raise no special safety concerns.

What does gene A do? What does gene B do? What does it do in different contexts? What's its importance? We know the answer to that for a very small number of genes, the ones that made themselves evident many years ago.

It's a very complex network of genes making products which go into the nucleus and turn on other genes. And, in fact, you find a continuing network of processes going on in a very complex way by which genes are subject to these continual adjustments, as you might say - the computer programmer deciding which genes ultimately will work.

The three of us have worked on the development of the small and totally harmless fruit fly, Drosophila. This animal has been extremely cooperative in our hands - and has revealed to us some of its innermost secrets and tricks for developing from a single celled egg to a complex living being of great beauty and harmony. ... None of us expected that our work would be so successful or that our findings would ever have relevance to medicine.

The future is to heal back to the mind again. Recognizing that the mind is all powerful - it controls every cell to every degree of its genetic expression.

After I arrived in Basel, I initially attempted to continue the project of my days in Dulbecco's laboratory, namely, the transcriptional control of the simian virus 40 genes.

It is easy to make out three areas where scientists will be concentrating their efforts in the coming decades. One is in physics, where leading theorists are striving, with the help of experimentalists, to devise a single mathematical theory that embraces all the basic phenomena of matter and energy. The other two are in biology. Biologists-and the rest of us too-would like to know how the brain works and how a single cell, the fertilized egg cell, develops into an entire organism

You would think that UV just causes mutations, but it doesn't; you need a gene to be active for it.

In any complex organism, brain formation and function must be controlled in part by genes.

Since the conventional belief about human embryology is that genes control the development of the fetus, the mother's role in her child's gestation is deemed to be not much more than providing nutrition, feeding her child.

We know specific genes are turned on in specific cells, but we don't know to what extent this happens.

We can change the expression of more than 70 percent of the genes that have a direct bearing on our health and longevity.

A functional biological clock has three components: input from the outside world to set the clock, the timekeeping mechanism itself, and genetic machinery that allows the clock to regulate expression of a variety of genes.

As has repeatedly been stated, the underlying hypothesis, which in a number of cases has been supported by direct experimental evidence, is that each gene controls the production, function, and specificity of a particular enzyme.

I don't believe biology works in an uncontrolled fashion.

I became fascinated by the then-blossoming science of molecular biology when, in my senior year, I happened to read the papers by Francois Jacob and Jacques Monod on the operon theory.

The identification of the genes which determine biological phenomena and the study of the control they exert on these phenomena has proven to be the most successful approach to a detailed understanding of the mechanism of biological processes.

The blooming of a flower is, in my mind, not a miracle. It's something that we can understand on the basis of molecular biology these days.

Furthermore, neither of our research groups set out in search of RNA catalysis.

Resveratrol does not act primarily as an antioxidant. It is far more interesting and powerful than that. Resveratrol turns on our body's genetic defenses against diseases and aging itself.

Genes are a play within a play, not the interior monologue of the players.

We can't any longer have the conventional understanding of genetics which everybody peddles because it is increasingly obvious that epigenetics - actually things which influence the genome's function - are much more important than we realised.