John Vane Quotes
It is sometimes said that the major discoveries have already been made and that there is nothing important left to find. This attitude is altogether too pessimistic. There are plenty of ideas and plenty of things left to discover. The trick is to find the right path from one to the other.
Vane, John R. "The Evolution of Drug Discovery." Journal of Physiology and Pharmacology, vol. 51, no. 4, 2000, pp. 573-587.
Scientific breakthroughs depend on genius, circumstances, the work of others and serendipity. None of these are very predictable which is why it is do difficult to manage a scientific enterprise and be accountable for any results. See {624867}.
Sir John Robert Vane FRS was a British pharmacologist who was instrumental in the understanding of how aspirin produces pain-relief and anti-inflammatory effects and his work led to new treatments for heart and blood vessel disease and introduction of ACE inhibitors. He was awarded the Nobel Prize in Physiology or Medicine in 1982 along with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances".