The world had teeth and it could bite you with them anytime it wanted.
Life on Earth is at the ever-increasing risk of being wiped out by a disaster, such as sudden global nuclear war, a genetically engineered virus or other dangers we have not yet thought of.
If you are designing cryptosystems, you've got to think about long-term applications. You've got to try to figure out how to build something that is secure against technology in the next century that you cannot even imagine.
Sometimes, our expectations of being all-knowing is somewhat unrealistic. At the end of the day, there are people out there who mean harm to us, are thinking about doing harm to us and motivated to do it, and we don't know what that is.
It is the things you cannot see coming that are strong enough to kill you.
We cannot stop what we cannot see.
The things we worry about the most are never the things that bite us. The sharpest teeth always take their nip of us when we are looking the other way.