Genetic Translation Quotes

It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

Do codons overlap? In other words, as we read along the genetic message do we find a base which is a member of two or more codons? It now seems fairly certain that codons do not overlap.

It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.

I wanted to reveal how genetic code is translated into protein. I knew a great application could be for antibiotics, since half of the useful ones target the ribosomes, but I didn't believe I could contribute to it. It was like the next Mount Everest to conquer. It was my dream to contribute something to humanity.

The ribosome is a machine that gets instructions from the genetic code and operates chemically in order to produce the product.

The convergence of information technology and biology allows scientists to translate the human genome into digital data that can accelerate diagnoses and cures.

Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.

DNA is a code of four letters; proteins are made up of amino acids which come in 20 forms. So the ribosome is a very clever machine that reads one language and operates in another.

I knew the ribosome was going to be the focus of Nobel prizes. It stands at the crossroads of biology, between the gene and what comes out of the gene. But I had convinced myself I was not going to be a winner.